I've had Fluke on my to-read list for a long time, but I was disappointed in the last Christopher Moore book I read, so hadn't really gotten around to this one.
I had thought the humor in the last one more than a bit labored, and at first I was pleasantly surprised with Fluke. It was funny, the characters engaging, and I was enjoying the noodling around. Unfortunately, at some point the plot started up and it all went to hell. The plot is kind of funny in a way, but I never really found myself laughing, and at the same time the writing seemed to get less funny.
In the end, I was back to my original opinion, and can't imagine I'll be reading more Christopher Moore.